Millions of people suffer from symptoms as a result of reflux, where the contents of the stomach pass through the lower oesophageal sphincter and into the oesophagus. This can be caused by various lifestyle and diet habits, and other things such as obesity, hiatus hernia and pregnancy. Reflux can be compounded by a weakened lower oesophageal sphincter too which enables the contents of the stomach to escape through the weakened valve more easily.

In some instances, reflux episodes can reach the larynx, pharynx and nasal cavity, causing extra-gastrointestinal symptoms (see below).

Left untreated, prolonged exposure of the different mucosa to the contents of reflux, the disorder can lead to Barrett’s oesophagus, oesophageal adenocarcinoma (cancer) and laryngeal cancer.

Symptoms of Reflux

Gastroenterological Symptoms of Reflux:

  • Heartburn

  • Difficulty swallowing (dysphagia)

  • Nausea and regurgitation

  • Vomiting

Ear, Nose and Throat (ENT) Symptoms of Reflux:

  • Sore throat or hoarseness

  • Chronic cough or persistent throat congestion

  • Asthma

  • Post nasal drip

  • Difficulty swallowing

Monitor disease activity

Diagnose difficult symptoms

Select appropriate


For GP and Specialist use

Diagnose Reflux with Peptest™

Until recently, reflux diagnosis involved complex and expensive procedures including 24/48 hour pH monitoring, pH Impedance testing, Barium meal and gastroscopy.

Peptest is a simple, effective and low cost test that tells you conclusively that a patient has reflux. By measuring Pepsin in saliva samples, it is a clear indicator that a reflux episode has occurred because pepsin is only produced in the stomach. If it is detected in the oesophagus, throat, mouth or lungs it identifies reflux and enables a swift and appropriate treatment plan to be made.

Peptest image


Kit for Labs

Set up Peptest in your own laboratory with ease

Peppak contents jpg 400 x 331.jpg

Peptest™ Service Laboratory

Send samples to our service laboratory for Peptest analysis

Frequently asked Questions

What is the accuracy of Peptest?

Why do my patients need to submit 3 samples?

What is the laboratory turnaround time?

Should the patient pause their PPI, H2RA, or antacid therapy for the test?

Can Peptest be used in the investigation of laryngopharangeal reflux (LPR)?

BIOHIT HealthCare in Reflux and Dyspepsia 

Millions of people in the UK and worldwide suffer from non-specific gastroesophageal symptoms which are challenging for the treating physician to manage. BIOHIT HealthCare has academic interest in dyspepsia as well as a commercial role in supplying innovative test systems to help physicians diagnose and monitor dyspepsia and associated diseases.


BIOHIT HealthCare supplies essential tests that help investigate dyspepsia in Primary and Secondary Care, helping treating physicians to adopt a test-and -treat or test-and-refer strategy to improve their practice. With BIOHIT's non-invasive GastroPanel and Peptest diagnostic tests, the treating physician can determine the health and function of the stomach prior to treating, and, gain a clear understanding of the involvement of acid and pepsin. The tests help physicians decide whether the patient should be referred to Secondary Care for further investigation or treated in Primary Care with confidence.


Contact Us

BIOHIT HealthCare Ltd

Pioneer House, Pioneer Business Park

North Road

Ellesmere Port

Cheshire CH65 1AD

United Kingdom

Tel: +44 151 550 4 550

Fax: +44 151 550 4 551

© 2020 BIOHIT HealthCare Ltd

  • LinkedIn
  • Twitter Social Icon