Millions of people suffer from symptoms as a result of reflux, where the contents of the stomach pass through the lower oesophageal sphincter and into the oesophagus. This can be caused by various lifestyle and diet habits, and other things such as obesity, hiatus hernia and pregnancy. Reflux can be compounded by a weakened lower oesophageal sphincter too which enables the contents of the stomach to escape through the weakened valve more easily.
In some instances, reflux episodes can reach the larynx, pharynx and nasal cavity, causing extra-gastrointestinal symptoms (see below).
Left untreated, prolonged exposure of the different mucosa to the contents of reflux, the disorder can lead to Barrett’s oesophagus, oesophageal adenocarcinoma (cancer) and laryngeal cancer.
Symptoms of Reflux
Gastroenterological Symptoms of Reflux:
Difficulty swallowing (dysphagia)
Nausea and regurgitation
Ear, Nose and Throat (ENT) Symptoms of Reflux:
Sore throat or hoarseness
Chronic cough or persistent throat congestion
Post nasal drip
Monitor disease activity
Diagnose difficult symptoms
For GP and Specialist use
Diagnose Reflux with Peptest™
Until recently, reﬂux diagnosis involved complex and expensive procedures including 24/48 hour pH monitoring, pH Impedance testing, Barium meal and gastroscopy.
Peptest is a simple, effective and low cost test that tells you conclusively that a patient has reﬂux. By measuring Pepsin in saliva samples, it is a clear indicator that a reflux episode has occurred because pepsin is only produced in the stomach. If it is detected in the oesophagus, throat, mouth or lungs it identifies reflux and enables a swift and appropriate treatment plan to be made.
Frequently asked Questions
What is the accuracy of Peptest?
Why do my patients need to submit 3 samples?
What is the laboratory turnaround time?
Should the patient pause their PPI, H2RA, or antacid therapy for the test?
Can Peptest be used in the investigation of laryngopharangeal reflux (LPR)?
BIOHIT HealthCare in Reflux and Dyspepsia
Millions of people in the UK and worldwide suffer from non-specific gastroesophageal symptoms which are challenging for the treating physician to manage. BIOHIT HealthCare has academic interest in dyspepsia as well as a commercial role in supplying innovative test systems to help physicians diagnose and monitor dyspepsia and associated diseases.
BIOHIT HealthCare supplies essential tests that help investigate dyspepsia in Primary and Secondary Care, helping treating physicians to adopt a test-and -treat or test-and-refer strategy to improve their practice. With BIOHIT's non-invasive GastroPanel and Peptest diagnostic tests, the treating physician can determine the health and function of the stomach prior to treating, and, gain a clear understanding of the involvement of acid and pepsin. The tests help physicians decide whether the patient should be referred to Secondary Care for further investigation or treated in Primary Care with confidence.