GA-Map™

Dysbiosis test

SIMPLIFYING MICROBIOTA TESTING

Microbiota and Dysbiosis

The medical and scientific community is showing a great deal of interest towards a condition known as dysbiosis, which can be described as a microbial imbalance within the body.

Dysbiosis of the gut flora has been linked to numerous medical conditions including Inflammatory Bowel Disease  (IBD) (ulcerative colitis (UC), Crohn’s disease (CD)), Irritable Bowel Syndrome (IBS), obesity, nonalcoholic steatohepatitis, and type I and type II diabetes.

The microbiota provides essential roles in normal physiology such as vitamin synthesis, digestion, and immunity. Bacteria that make up the human microbiota in the gut out number human cells 10:1 and it has been shown that alterations in the gut microbiome are associated with functional gastrointestinal disorders (FGID), obesity, diabetes and cancer. Through microbiota research emerging strategies to treat FGID such as the use of pre- and pro-biotics, antibiotics and faecal microbiota transplants (FMT) are bringing new options for patients and providers dealing with chronic digestive disorders.

Analyse your patients' microbiota

Traditionally, the identification of dysbiosis has been based on breath-testing methods and small-bowel culture techniques, which are insufficiently validated and give a less thorough picture of the gut microbiota. To overcome these challenges, BIOHIT, together with Norwegian company Genetic Analysis AS, has introduced the GA-map™ Dysbiosis test, which is the first CE marked gut microbiota DNA analysis tool to identify and characterise dysbiosis from a faecal sample. This test provides a rapid, high-throughput analysis of a large number of individual faecal samples and provides a standardised approach to microbiome analysis.

Microbiota analytical Services at BIOHIT HealthCare

Clinicians and Practitioners can arrange for patient samples to be sent to our laboratory for microbiota analysis using the GA-Map dysbiosis test. Sending samples to BIOHIT for analysis is easy and can be used for routine clinical applications or for research. The main benefit of using the GA-Map technology over other applications (e.g. sequencing) is in the standardisation and consistency of results with simple data reduction. Results are presented in an easy to read format and include a comprehensive profile of the patient's microbiota. Results also include an indication of dysbiosis based on the relative abundance of individual bacteria compared to a healthy (control) population.

Access the service in four simple steps:

1

Fill out the Test Request Form

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Your patients will need a completed Test Request Form before taking the GA-Map Dysbiosis Test. The form should be completed by the requesting physician and the patient.

2

Order Sample Collection Kit

Once your patient has a completed test request form it's time to order their sample collection kit. This can be done via our online order form or through your practice.

3

Patient collects a stool sample

Give the patient a Sample Collection Kit along with a copy of their completed Test Request Form and they can collect a stool sample in the comfort of their home. When the patient packages their sample for shipping they must include the Test Request Form.

4

Send sample to our lab

Patients can book our courier to pick up their sample from a nominated address at a time convenient to them by completing our easy to use web-form, or by calling customer services.

For Research

Faecal microbiota analyses requires expert input to get high quality and reproducible data. Accessing a microbiota analytical service or setting up the technology to perform your own analyses can be a costly process and often lacks the valuable experience needed to interpret the data.

BIOHIT HealthCare can help with research applications that require professional microbiota analysis delivered by experts in the field. We collaborate with researchers like you to build the evidence needed to bring benefit to patients from diagnostic and therapeutic interventions that involve analysis and manipulation of the microbiome.

If you are interested in analysing microbiota as part of your clinical or academic research let us know and we will be glad to help.

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© 2018 BIOHIT HealthCare Ltd

Contact Us

BIOHIT HealthCare Ltd

Pioneer House, Pioneer Business Park

North Road

Ellesmere Port

Cheshire CH65 1AD

United Kingdom

Tel: +44 151 550 4 550

Fax: +44 151 550 4 551

cs@biohithealthcare.co.uk

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