Stomach health, Dyspepsia and Acid Dysregulation

Dyspepsia is a broad term often used to describe functional gastrointestinal disorders of the stomach and oesophagus. It is well known that the clinical symptoms which fall under the term dyspepsia contribute to a significant population-wide health problem. Individuals who suffer with heartburn, reflux, indigestion, and stomach pains are assessed based on their clinical presentation, lifestyle and family history in a bid to determine the risk of disease.


The majority of patients categorised as having functional dyspepsia are treated with strong antacids (e.g. omeprazole, lanzoprazole) before any diagnostic tests are used in an attempt to alleviate symptoms. This is because when it comes to investigating the cause of the symptoms in Primary Care, until recently physicians have had very limited access to reliable tests to help  diagnose stomach disease without referring to Secondary Care. Experts agree that symptoms are a poor predictor of significant disease or underlying pathology and so more is needed to enable GPs to make positive diagnoses of important pathologies to identify those patients at risk.​​

About dyspepsia

  • There are three main categories of dyspepsia defined by:

    • Gastroesophageal Reflux Disease (GORD)

    • Peptic ulcer disease

    • Functional dyspepsia

  • Dyspepsia is not always associated with excessive acid production

  • Traditional tests for dyspepsia include:

    • Evaluation of H. pylori status​

    • pH testing

    • Endoscopy

  • New tests for dyspepsia are linked to risk:​

    • GastroPanel (combinations of H. pylori, Pepsinogens and Gastrin 17 tests)

    • Peptest (detection of pepsin in refluxate and saliva)

Diagnostic tests and products that help GPs manage dyspepsia

GastrPanel first line test for dyspepsia in prmary care


stomach health test

Diagnose dyspepsia and select patients for endoscopy

Non-invasive diagnosis of reflux in primary care


reflux diagnosis

Diagnose reflux disease non-invasively

ACETIUM for acetaldehyde elimination


for achlorhydria

Explore a new option for individuals with atrophic gastritis or taking PPIs

Prioritise referrals

Non-invasive tests

Primary Care setting

Appropriate prescribing

Millions of people experience non-specific stomach complaints from time to time, or even on daily basis. Less than half will seek medical advice and for those that do, clinical assessments can be challenging for the treating physician. Stomach problems may present as pain or discomfort, with or without heartburn, a feeling of heaviness, bloating, nausea or vomiting. On the other hand, sometimes severe diseases that require medical investigation manifest silently, and so basing a diagnosis on clinical symptoms alone is often insufficient. Ensuring that you get accurate information on the status of your patients' stomachs can significantly help manage the patient and improve outcomes.

BIOHIT HealthCare supplies essential tests that help investigate dyspepsia in Primary Care, helping treating physicians to adopt a test-and -treat or test-and-refer strategy to improve their practice. With BIOHIT's GastroPanel and Peptest, the physician can determine the health and function of the stomach prior to treating, and, gain a clear understanding of the involvement of acid and pepsin. The test will help the physician decide whether the patient should be referred to Secondary Care for further investigation or treated in Primary Care with confidence.