Investigating Small Bowel Disorders
Disorders and diseases of the small intestine are common and diverse. The small intestine is large (long) organ made up of three parts defined anatomically and by the role they play in digestion:
Disorders that originate in the small intestine include bleeding, ulcers, IBD, coeliac disease, enteritis/infection, cancer, obstruction as well as functional gastrointestinal disorders (FGID). Any disorder that affects the mucosal architecture of the small intestine can affect the absorption of nutrients and lead to further disorders characterised by malabsorption. For example, Coeliac disease is a condition that affects around 1% of the population where individuals elicit an immune response to dietary gluten that causes atrophy to the intestinal mucosa. The atrophied mucosa loses the ability to absorb essential nutrients and can lead to weight-loss, failure to thrive, anaemia, bone abnormalities and osteoporosis, vitamin and mineral deficiency, and neuropathy.
BIOHIT HealthCare supplies a range of assays for the investigation of small bowel disorders both for routine and research use.