Unified Pepsinogen I ELISA Kit, 96 wells

Product family:
Product Code:

Product Information:

The BIOHIT Unified Pepsinogen I ELISA is part of the GastroPanel® family of assays - a simple blood test for Primary Care that aids the diagnosis of dyspepsia by effectively ruling out diseases of the gastric mucosa characterised by Helicobacter pylori (H.pylori) infection and atrophic gastritis.

Pepsinogen I concentration in blood reflects the mucosal structure and function of the gastric body (corpus). Infection with Helicobacter pylori or autoimmune disease can cause moderate to severe atrophy of stomach body mucosa (atrophic gastritis of corpus). Then follows a fall in blood Pepsinogen I levels below 30 µg/l, and results in an acid-free or low-acid stomach. In contrast, if the patient has inflammation of stomach body mucosa, but no atrophy (gastritis of corpus), the blood Pepsinogen I concentration tends to increase to some extent.

The Pepsinogen I/II ratio is used together with Pepsinogen I value for diagnosis of atrophy of the gastric body mucosa (atrophic gastritis of corpus). In the case of atrophic gastritis of corpus, the ratio decreases below 3.

Use Pepsinogen I as part of the complete GastroPanel® to help diagnose:


  • Healthy stomach mucosa. When the stomach mucosa is healthy, the cause of stomach symptoms is most likely to be functional dyspepsia or disease outside the stomach.

  • Acid dysregulation

  • H. pylori infection

  • Atrophic gastritis (severely damaged and dysfunctional stomach mucosa) and specifically the location of the disease, e.g. corpus, antrum, or both mucosa


GastroPanel® consists of four ELISAs and can be set up in any local laboratory or can be requested via BIOHIT's Service Laboratory.


  • Monoclonal Ab Sandwich ELISA specific for Pepsinogen I

  • Protocol harmonised with other Unified GastroPanel ELISAs

  • 1 blank, 3 calibrators

  • 1 controls

  • Capacity for 43 samples in duplicate

  • Total incubation time 150 minutes

  • Broad linear range (1.9 - 200μg/l)

  • Easily Automated on ELISA automate (e.g. Dynex DS2)


Please refer to Unified GastroPanel (Product Code 606400)



Storage (°C)

+2 to +8

Sample type





Contact Us

BIOHIT HealthCare Ltd

Pioneer House, Pioneer Business Park

North Road

Ellesmere Port

Cheshire CH65 1AD

United Kingdom

Tel: +44 151 550 4 550

Fax: +44 151 550 4 551


© 2020 BIOHIT HealthCare Ltd

  • Twitter Social Icon