IDKmonitor Golimumab Free Anti-drug antibody ELISA 96 wells

Product family:
Product Code:
Therapeutic Drug Monitoring

Product Information:

Golimumab is a recombinant protein that has the potential to induce humoral immune responses and lead to anti-drug antibody formation; a major cause of loss of response.


These Anti-drug antibodies bind and neutralise the TNFα inhibitors accelerating their clearance and reduces the efficacy of the drugs.  Monitoring the efficacy of TNFα inhibitors may help clinicians schedule a successful individualised treatment strategy for their patients.

Free Anti-Golimumab Antibody ELISA

Free anti-drug antibody ELISAs ("drug sensitive assays") enable the detection of anti-drug antibodies that are not bound to other proteins or therapeutic drugs.

IDKmonitor® Golimumab Free Anti-drug Antibody ELISA is a qualitative assay that detects human antibodies against Golimumab in EDTA plasma and serum samples by capturing the anti-Golimumab antibodies on the microplate which is coated with Golimumab F(ab)2 fragments.


  • Detects free anti-Golimumab Antibodies in Serum and Plasma

  • Microplate coated with highly specific Golimumab F(ab)2 fragments

  • 1 calibrator, 2 controls

  • Capacity for 45 samples in duplicate

  • Assay time 130 minutes

  • Automatable on ELISA automates (e.g. Dynex DS2)


  • Supports the investigation of primary non response and loss of response to Golimumab

  • Drug sensitive assay only detects free anti-golimumab antibodies (those not bound to golimumab)

  • May help predict long term outcome of disease in patients with sub-therapeutic golimumab levels

  • Available via reference laboratories in UK

  • Applicable to Gastroenterology, Rheumatology



Storage (°C)

+2 to +8

Sample type