IDKmonitor Golimumab Drug Level ELISA 96 wells

Product family:
Product Code:
Therapeutic Drug Monitoring
K9656

Product Information:

The IDKmonitor Golimumab Drug Level ELISA kit is a microplate-based quantitative enzyme linked immunosorbent assay (ELISA) for the determination of free Golimumab from plasma or serum samples.

The Golimumab ELISA is based on a sandwich enzyme immunoassay technique with a Golimumab specific capture antibody adsorbed on a microplate and a detection antibody labeled with horseradish peroxidase (HRP).

This test is intended to quantify the amount of free drug (Golimumab) to evaluate the efficacy of drug and to investigate Primary non-response and loss of response.

Being able to stratify patients according to whether they are likely to benefit from their Golimumab treatment has both clinical and economic advantages because not all patients respond equally to Golimumab.

Some patients will respond well with fewer symptoms with a reduction in inflammatory biomarkers (e.g. faecal calprotectin) and endoscopic scores, while others will fail to respond during the induction phase of treatment, or lose response over time.

IDKmonitor® assays from BIOHIT HealthCare are highly specific for the target drug and are used widely for routine clinical and research applications. The IDKmonitor® Golimumab Drug Level ELISA helps:

  • Assess risk of and manage primary non-response

  • Predict the long term outcome and identify loss of response

  • Predict response to anti-TNFα therapy withdrawal

  • Predict efficacy of re-initiating therapy after drug holiday

  • Direct the switching to another class of drug

The IDKmonitor® Golimumab Drug Level ELISA is for the quantitative determination of free therapeutic TNFα antibodies (Golimumab (e.g. SIMPONI®)) in EDTA plasma and serum. The assay detects and quantifies free Golimumab from a sample by capturing it using specific monoclonal anti-Golimumab antibody that coats the plate.

The assay is widely available throughout the UK and Ireland to both routine clinical laboratories as well as for research applications. Please contact us for your nearest test reference laboratory.

Features:

  • Quantifies free Golimumab drug levels in Serum and Plasma

  • Microplate coated with highly specific anti-Golimumab Ab

  • 6 calibrators, 2 controls

  • Capacity for 40 samples in duplicate

  • Reportable range 4.15-225 ng/ml

  • Total incubation time 130 minutes

  • Automatable on ELISA automates (e.g. Dynex D2)

Benefits:

  • Highly specific quantification of Golimumab

  • Helps predict Primary non-response, loss of response, non remission

  • Available via reference laboratories in UK

  • Applicable to Gastroenterology, Rheumatology

Format

ELISA

Storage (°C)

+2 to +8

Sample type

Blood

Category

Laboratory

Index

© 2018 BIOHIT HealthCare Ltd

Contact Us

BIOHIT HealthCare Ltd

Pioneer House, Pioneer Business Park

North Road

Ellesmere Port

Cheshire CH65 1AD

United Kingdom

Tel: +44 151 550 4 550

Fax: +44 151 550 4 551

cs@biohithealthcare.co.uk

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