IDKmonitor Etanercept Free Anti-drug antibody ELISA 96 wells

Product family:
Product Code:
Therapeutic Drug Monitoring
K9653

Product Information:

Etanercept is a recombinant protein that has the potential to induce humoral immune responses and lead to anti-drug antibody formation; a major cause of loss of response.

 

These Anti-drug antibodies can bind and neutralise the drug accelerating its clearance and reducing its efficacy.  Monitoring the efficacy of Etanercept may help clinicians schedule a successful individualised treatment strategy for their patients.

Free Anti-Etanercept Antibody ELISA

Free anti-drug antibody ELISAs ("drug sensitive assays") enable the detection of anti-drug antibodies that are not bound to other proteins or therapeutic drugs.

IDKmonitor® Etanercept Free Anti-drug Antibody ELISA is a quantitative assay that detects human antibodies against Etanercept in EDTA plasma and serum samples by capturing the anti-Etanercept antibodies on the microplate which is coated with Etanercept binding domains.

Features:

  • Detects free anti-Etanercept Antibodies in Serum and Plasma

  • Microplate coated with highly specific Etanercept fragments

  • 1 calibrator, 2 controls

  • Capacity for 45 samples in duplicate

  • Assay time 130 minutes

  • ?Automatable on ELISA automates (e.g. Dynex D2)???

Benefits:

  • Supports the investigation of primary non response and loss of response to Etanercept

  • Drug sensitive assay only detects free anti-Etanercept antibodies (those not bound to Etanercept)

  • May help predict long term outcome of disease in patients with sub-therapeutic Etanercept levels

  • Applicable to Rheumatology

Format

ELISA

Storage (°C)

+2 to +8

Sample type

Blood

Category

Laboratory

Index

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BIOHIT HealthCare Ltd

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Ellesmere Port

Cheshire CH65 1AD

United Kingdom

Tel: +44 151 550 4 550

Fax: +44 151 550 4 551

cs@biohithealthcare.co.uk

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