Lactose intolerance (hypolactasia) results in the inability to digest lactose, the predominant sugar of milk. This inability results from a shortage of the lactase enzyme in the small intestine. Lactase deficiency is also known as lactase non-persistence.

Lactase enzyme breaks down milk sugar (lactose) into simpler forms (glucose and galactose), which can then be absorbed into the bloodstream.

 

Lactase activity begins to decrease after weaning due to a natural down regulation of the lactase gene. One-third of the adult population worldwide retains the ability to digest lactose. It is estimated that approximately 15-20% of Western and Northern Europeans, and 90% of Asian, African and native Americans suffer from lactose intolerance. Often the symptoms remain undiagnosed, and, thus lactose intolerance may not be treated for years.

 

Individuals who suffer from lactae deficiency often present with symptoms similar to IBS which include:

 

  • nausea

  • flatulence

  • abdominal discomfort, cramps and bloating

  • diarrhoea

 

Such symptoms can result from intestinal bacteria that hydrolyse ingested lactose to glucose and galactose, which are in turn fermented by the gut flora to produce short chain fatty acids, Hydrogen, and Methane. Lactose itself also has a high osmotic effect which can cause diarrhoea.

 

Clinical Benefits of the Lactose Intolerance Quick Test

 

  • Rule out Lactase deficiency as a cause of IBS symptoms

  • Identify Primary, Secondary, Congenital and Familial Lactase Deficiency

  • More accurate than alternative methods

  • Based on the Gold Standard biopsy dissaccharidase test

  • Sensitivity 95%, Specificity 100%

Lactose Intolerance Quick Test, 25 Tests

Product Code

602010

Clinical Background

Index

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