The antral gastric hormone gastrin (gastrin-17) regulates gastric acid secretion and growth of the gastric mucosa. As a result of the cellular posttranslational maturation process of progastrin, the G cells in the antrum release a mixture of different acid  stimulatory gastrins and other precursor fragments into the circulation. G-17 is the predominant and potent tissue form in healthy antral mucosa and almost exclusively produced by the antrum G-cells and can be measured serologically. However Gastrin-17 in plasma is relatively labile and so requires careful preparation to preserve its concentration in blood samples in order to obtain a reliable measurement.

Gastrin 17 Stabiliser, 1 x 5.5 ml

Product Code

601050

Clinical Background

Index

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